Mupirocin ointment is a prescription topical antibiotic used to treat bacterial skin infections like impetigo, folliculitis, and secondary infected traumatic lesions (cuts or scrapes) caused by Staphylococcus aureus or Streptococcus pyogenes. It works by inhibiting bacterial protein synthesis. Commonly applied three times daily for up to 10 days, it is generally safe for adults and children.

Key Details About Mupirocin Ointment

• Mechanism of Action: It is a topical antibacterial agent that binds to bacterial isoleucyl-tRNA synthetase, stopping bacterial protein and RNA synthesis, leading to bacteriostasis.

• Uses: Effectively treats primary skin infections (impetigo) and secondary skin infections (e.g., infected eczema or wounds). It is also used to eradicate nasal colonization of MRSA.

• Application: A small amount is applied to the affected area 3 times a day, often for 1–2 weeks. The area may be covered with a gauze dressing.