Tenofovir Disoproxil Fumarate, Lamivudine, and Efavirenz is a prescription combination medication used as a complete regimen for the treatment of Human Immunodeficiency Virus type 1 (HIV-1) infection in adults and adolescents weighing at least 35 kg. It is not a cure for HIV or AIDS. 

Key Information

• Mechanism: The medication combines three antiviral medicines from two different classes: efavirenz (a non-nucleoside reverse transcriptase inhibitor) and lamivudine and tenofovir disoproxil fumarate (nucleo[t]side reverse transcriptase inhibitors). They work by blocking an enzyme (reverse transcriptase) that HIV needs to make copies of itself, thereby reducing the amount of virus in the body and helping the immune system work better.

• Dosage: It is typically a once-daily oral tablet taken on an empty stomach, preferably at bedtime, to reduce certain side effects.